State schemes, ongoing and completed projects

Ongoing Outside Funded Projects

Livestock Health and Disease Control Programme on FMD “Foot-and Mouth Disease - Hisar Centre" funded by ICAR
Centre of Advanced Faculty Training in Veterinary Microbiology Sponsored by ICAR, New Delhi (Since 1995)
Production and characterization of FMDV specific Nbs for application as diagnostic reagents funded by HSCSIT, Haryana
Seromonitoring of FMD+HS combined vaccination in livestock population of Haryana funded by HLDB

Ongoing State Funded Projects

Studies on Infection and Immunity in relation to Foot and Mouth disease virus and HaemorrhagicSepticaemia

Ongoing Institutional Projects:

Development of Real-time PCR assay for detection of Porcine Rotavirus funded by LUVAS
Expression and characterization of scFv clones selected against FMD serotype “O” from bovine scFv-phage display library funded by LUVAS

Completed Projects

Sr. No.	Title of the project	Funding agency
1	Studies on Salmonella Infections in Domestic Animals and Birds	USAID (PL-480)
2	Research on Salmonellosis	ICAR, New Delhi
3	Studies on Equine Rhinopneumonitis Virus (EHV-1).	ICAR, New Delhi
4	Studies on Enteroviruses of Goats and Sheep in Relation to Diarrhoea and Pneumonia. (National Fellow Scheme)	ICAR, New Delhi
5	Molecular Biochemistry and Immunology of Salmonella Associated Diarrhoea. (National Fellow Scheme)	ICAR, New Delhi
6	Studies on Some Aspects of Viral Diarrhoea in Cattle and Buffalo Neonatal Calves. (National Fellow Scheme)	ICAR, New Delhi
8	Enterobacteriacae and Other Diarrhoea Producing Bacteria with Special Reference to their Studies on Determinants of Pathogenicity and Immunity.	ICAR, New Delhi
9	Studies on Animal Pox Group of Viruses with Special Reference to Production of Vaccine Against Sheep Pox Virus.	Haryana State
10	Studies on Bluetongue Virus Infection in Livestock.	Haryana State
11	Studies on Viral Etiology of Respiratory Infections in Bovines.	Haryana State
12	Immunobiology of Important Farm Animals.	Haryana State
13	Studies on Chronic Respiratory Diseases of Poultry with Special Reference to the Development of Suitable Diagnostic Antigen and Vaccine for Immunization.	Haryana State
14	Epidemiology and Immunobiology of Bluetongue Virus.	USAID (PL-480)
15	Development of Immunodiagnostics Against Sheep Pox using Monoclonal Antibodies.	Indo-USSR
16	Immunity and Monoclonal Antibodies Against EHV-1.	UGC, New Delhi
17	Development of a Monoclonal Antibody and Outer Membrane Protein(s) based ELISA Kit for Monitoring Immune Status of Animals Vaccinated Against Hemorrhagic Septicemia.	DBT, GOI, New Delhi
18	Characterization of Virulence Factors Associated with Avian Pathogenic Escherichia coli Isolated from Respiratory Disease Complex.	UGC, New Delhi
19	Production of Phage Display Library of Single-Domain Antibodies of LPS-Immunized Indian Desert Camel for Diagnostic & Therapeutic Use.	DBT, GOI, New Delhi
20	Peste des Petit Ruminants in Goats and Sheep	HLDB,Chandigarh
21	Production and Use of a Diagnostic Kit for “Surra” Caused by Trypanosoma evansi in Various Animal Species	RKVY, SLFC, Haryana Govt.
22	Control of Hemorrhagic Septicemia (HS) in Cattle and Buffaloes in the State of Haryana.	RKVY, SLFC, Haryana Govt.
23	Development of a Therapeutic Antibody as a Drug for Treatment of Endotoxemia in Domestic Animals	RKVY, SLFC, Haryana Govt.
24	Socio-economic Impact of FMD Control in India	ICAR, New Delhi
25	Foot and Mouth Disease Control Programme	ICAR, New Delhi
26	Niche Area of Excellence (NAE) Project on “Phage Display Techniques for Production of Veterinary Immunobiologicals without Sacrificing Animals”	ICAR, New Delhi
27	Treatment of Endotoxaemia in buffalo calves by single domain antibody	RKVY, SLSC, Haryana
28	Establishment of Molecular Diagnostic Facilities and Strengthening of Sero-monitoring Activities for Foot-and-Mouth Disease, Haemorrhagic Septicaemia and Brucellosis in Haryana	RKVY, SLSC, Haryana
29	Epidemiological Studies on pathogens associated with swine mortality and socio-economic upliftment of scheduled caste Pig farmers	RKVY-RAFTAAR, Haryana
30	Establishment of Immunohistochemical laboratory and strengthening of Immunotechnology laboratory for diagnosis of diseases of animals and poultry	RKVY, Haryana
31	Production and Diagnostic Applications of Immuno-biologicals for Infectious Diseases of Livestock	ICAR Emeritus Scientist Scheme
32	Release of funds for SCSP activities	ICAR, New Delhi
33	Production and applications of bovine interleukin-17 and anti IL-17 monoclonal antibodies	ICAR, New Delhi
34	Comparative Studies on Post-vaccinal Humoral Immune Response in FMD+HS combined, FMD alone and HS alone Vaccinated Buffalo Calves at SCBP, Sector-II, Sirsa Road, Hisar	GoI/ICAR
35	Implementation of HS + FMD Dual Vaccine in the State of Haryana	RKVY, Haryana

Technologies/ Products developed/ Trainings Imparted

ELISA Kit for Monitoring HS Immunity in Cattle and Buffaloes
Monoclonal Antibody Based Latex Agglutination Test for HS Diagnosis (Patent filed vide application no. 767/DEL/2015 dated March 20,2015)
DIVA test (3A-NSP antigen based ELISA) as per OIE protocol in collaboration with FreidrichLoeffler Institute, Greifswald, InselRiems, Germany for differentiation of FMD infected and vaccinated animals (DIVA strategy).
Monoclonal Antibody Specific to Trypanosoma evansi Circulating Antigen Produced by Hybridoma Technology. [Displayed as commercializable technology by Business Planning & Development Project (ICAR), CCSHAU/LLRUVAS, Hisar]
Phage Display Library of >107 Single-domain Antibodies of Lipopolysaccharide Immunized Indian Desert Camel. [Deposited in VTCC, NRCE, Hisar]
Single-domain Antibody Clones Specific to E. coli Endotoxin Selected from Phage Display Library of Indian Desert Camel. [Deposited in VTCC, NRCE, Hisar]
Single-domain Antibody Clones Specific to Staphylococcus aureus Beta-hemolysin Selected from Phage Display Library of Indian Desert Camel. [Deposited in VTCC, NRCE, Hisar]
Silver Impregnated Polyacrylamide Gels for Topical Applications. [Singh, A. 2011. J. Appl. Polym. Sci. 119 (2): 1084-1089]
Developed Four Important Hybridoma Clones Secreting Monoclonal Antibodies: Buffalo specific Antibody, Antibody Cross Reacting with Cattle and Buffalo Serum, Agglutinating Anti Pasteurella multocida Antibody and P.multocida B;2 Specific Antibody
Developed a Monoclonal Antibody Based ELISA for Monitoring HS Immunity Levels in Cattle and Buffaloes. {The test is being regularly used, since 2006, to monitor HS immunity status in cattle and buffaloes of the Haryana state}
Developed a Monoclonal Antibody Based ELISA and a Latex Agglutination Test for HS Diagnosis
On the basis of data generated by the Scientists of the Department, the Government of India has permitted Government of Haryana to vaccinate the Cattle and Buffaloes with Combined HS + FMD vaccine under NADCP as pilot project
One Week Training on “Phage Display Technology and its Applications” from March 02-07, 2020 under ICAR Niche Area of Excellence project.
Four trainings, each training of five days on “Skill development in animal health for scheduled caste livestock farmers” from 21^st-25^thMarch 2022 (three trainings) and 26^th-30^th March 2022 (one training) under SCSP, DFMD-ICAR.
National level “Capacity building/ training programme on probang/ oropharyngeal fluid (OPF) collection, dispatch, and follow-up of FMD NSP reactors” from 25-27 July 2023 sponsored by ICAR-National Institute on FMD, Bhubaneswar

Innovations in Teaching:

Practical manuals prepared for all the UG courses
Book on ‘Fundamental techniques in Immunology & Serology’ published from India and ‘Insight into influenza viruses of animals and humans’ published by Springer International publishers, Switzerland have been published.
Contributed to a large number of book chapters published from India and Abroad
Revision, reorganization & devising of All India common PG courses for MVSc and PhD as directed by ICAR 2008
Revision, reorganization & devising of All India common UG courses for BVSc & AH as directed by Veterinary Council of India MSVE 2016.
Organised 37 training courses for the faculty of SAUs/ SVASUs/ and ICAR institutes since 1995 under the aegis of the ICAR-CAFT.
Revision, reorganization & devising of All India common PG courses for MVSc and PhD as directed by ICAR BSMA 2023